Symptom Checklist
Organize what you notice before you talk with a clinician
Last reviewed: October 2026 · 43 sources
Educational only. This checklist does not diagnose anything. It can’t tell you whether you have any condition, and it doesn’t score your risk or say how likely anything is. The symptoms below are reported in published sources for mold-related illness, CIRS, MCAS, POTS, hEDS and multiple chemical sensitivity (MCS), but they overlap heavily with each other and with many other causes, such as thyroid problems, anemia, sleep disorders and depression [1]. Use it to organize what you notice, then talk with your doctor or another licensed clinician.
When to get urgent help
Don’t use this checklist in an emergency. Call 911 or your local emergency number if you or someone with you has:
- Signs of a severe allergic reaction (anaphylaxis), such as trouble breathing, wheezing or high-pitched breathing sounds, trouble swallowing, swelling of the face, eyes or tongue, slurred speech, or passing out. Use epinephrine if your clinician has prescribed it [2].
- Sudden crushing, squeezing or pressure in your chest, or sudden sharp chest pain with shortness of breath [3].
- Severe shortness of breath at rest, bluish lips or face, or drowsiness or confusion with breathing trouble [4].
- Fainting where the person is injured or bleeding, doesn’t become alert within a couple of minutes, is pregnant, or has chest pain, a pounding or irregular heartbeat, loss of speech, vision problems or can’t move a limb [5].
Even when it isn’t an emergency, see a clinician soon if you have never fainted before, faint often, or have new symptoms with fainting [5]. If you are having thoughts of suicide, call or text 988 in the U.S. [6].
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How to use this checklist
- Check anything you’ve noticed, now or in the past. Skip anything you’re unsure about.
- Under each item you’ll see which conditions our sources list it for, with numbered citations.
- Your results update as you go, in the Your results section below.
- Add your own notes, then print the summary or save it as a PDF to bring to your appointment.
What the tags mean
Each item lists the conditions where at least one cited source mentions it. Some tags carry a short note:
- Mold toxicity, allergy-type: symptoms health agencies link to mold allergy and damp buildings [7, 8].
- Mold toxicity, clinician-reported, debated: symptoms described by clinicians who treat mold-related illness [9]. Other experts say there is no scientific evidence linking mold to symptoms like these [10], and the AAAAI says mold allergy is “not usually a cause of chronic symptoms such as headache and fatigue” [8].
- CIRS, Surviving Mold list: from the 37-symptom list in the Surviving Mold consensus statement [11]. CIRS is debated in mainstream medicine [10, 12].
- MCAS, typical episode: symptoms of the sudden episodes described in the stricter consensus criteria [13].
- MCAS, broader model: symptoms listed by clinicians who use a broader “mast cell activation disease” model [14] or by The Mast Cell Disease Society [15]. Under the stricter criteria, many of these aren’t considered suggestive of MCAS [13].
- MCAS, listed trigger: possible mast cell triggers listed by The Mast Cell Disease Society [15].
- POTS and hEDS: from patient-organization pages, expert consensus statements and reviews [16, 17, 18, 19].
- MCS / chemical sensitivity, reported with chemical exposures: symptoms the Job Accommodation Network lists for multiple chemical sensitivity, which people report when exposed to things like fragrances, cleaning products, smoke or paint [39]. The smells item also reflects the 1999 consensus criteria and a U.S. survey [40, 41]. There’s no validated test for MCS [42], and ACOEM says evidence does not exist to define it as a distinct disease [43].
Your results
Please read: this is not a diagnosis. These lists only show which of the items you checked appear in the cited sources for each condition. They are not a score and don’t say how likely any condition is. Many of these symptoms have other common causes [1, 28], so checking a lot of items doesn’t mean you have a condition, and checking only a few doesn’t rule one out. The conditions always appear in the same order. Bring your summary to a clinician who can look at the whole picture.
No items checked yet.
Check items in the list above and your results will appear here.
Mold toxicity
Keep in mind: Health agencies link damp, moldy buildings mainly to nose, throat, eye, skin and breathing symptoms, and the CDC says they “may cause a variety of health effects, or none at all” [7]. Whether mold causes a broader, long-lasting illness is debated [9, 10].
CIRS
Keep in mind: These items come from the Surviving Mold symptom list [11]. Many mainstream doctors are unfamiliar with CIRS or don’t accept it as a diagnosis, and critics describe symptoms like these as vague and hard to measure [10, 12]. This checklist does not apply the CIRS cluster count or any other diagnostic rule.
MCAS
Keep in mind: Under the stricter consensus criteria, MCAS means sudden, recurring episodes that affect at least two body systems, with a measurable rise in mast cell markers and a response to medicines that block mast cell chemicals [13, 29]. Broader models list many more symptoms [14], but under the stricter criteria fatigue, headache, brain fog, joint pain, bloating and constant symptoms are not considered suggestive of MCAS [13].
POTS
Keep in mind: POTS is diagnosed by measuring heart rate and blood pressure lying down and then standing [16], and clinicians first look for other causes of a fast heart rate, such as dehydration, anemia, infection or an overactive thyroid [22].
hEDS
Keep in mind: hEDS is diagnosed with a clinical checklist that has three required parts [24]. Flexible joints alone aren’t hEDS: hypermobility is found in up to about 20% of people and often causes no problems [30].
MCS / chemical sensitivity
Keep in mind: These items are symptoms the Job Accommodation Network lists for MCS [39]. There’s no validated diagnostic test for MCS [42], and ACOEM says evidence does not exist to define it as a distinct disease [43]. Because these symptoms have many possible causes, a medical evaluation should look for conditions that can be diagnosed and treated [43].
Other common causes worth asking about
Symptoms like the ones you checked also have many causes outside these five conditions. Based on the sections you used, these are worth raising with your clinician:
Energy, sleep and thinking
- Anemia (low red blood cells) or low iron [1, 31].
- An underactive or overactive thyroid [1, 32, 33].
- Sleep problems such as insomnia or sleep apnea [1, 34].
- Depression or grief, which can also affect concentration, memory and sleep [1, 35].
- Side effects of medicines, including some antihistamines, blood pressure medicines, sleeping pills and steroids [1].
- Long-lasting infections, diabetes, autoimmune diseases and other illnesses [1].
Dizziness and heart rate
- Dehydration, a sudden drop in blood pressure, low blood sugar, or medicines that lower blood pressure [28].
- Anemia, fever, pain, infection, an overactive thyroid, some medicines, anxiety disorders, eating disorders or deconditioning after long bed rest. Clinicians check for these before diagnosing POTS [22].
- Inner-ear problems, which can cause vertigo [28].
- Heart rhythm problems and other heart conditions [28].
Skin and allergy-type reactions
Stomach and gut
Joints and muscles
Questions you could ask
- What else could be causing these symptoms, and which tests would help sort that out?
- Could any of my medicines or supplements be playing a part?
- Would it help to see a specialist? If so, what kind?
- What should I keep track of before my next visit, and when should I come back sooner?
- Would it make sense to check my heart rate and blood pressure lying down and then standing (an “active stand test”)? [16]
- If I have another sudden episode, should I get a tryptase blood test within about 4 hours, and how would I arrange that? [13]
- Would an assessment for joint hypermobility using the 2017 hEDS criteria be appropriate? [24]
- Could allergy testing help show whether mold or something else is behind my nose, eye or breathing symptoms? [8]
- Is there anything I should know about my health before cleaning up mold or water damage? [23]
- What do you think about the CIRS model, and what would you want to rule out first?
- Could another condition, such as asthma or allergies, explain my reactions to fragrances or chemicals, and how would we check? [43]
Urgent? Call 911 or your local emergency number for trouble breathing, swelling of the face, tongue or throat, chest pain or pressure, or fainting with an injury. See When to get urgent help.
Your “bring to your doctor” summary
Add anything else you want to mention, such as when symptoms started, what makes them better or worse, and any medicines or supplements you take. Your notes stay on this page only.
Want room for a symptom log, medicines, past tests and questions? Use our Doctor Visit Prep Sheet. Your answers here aren’t carried over (nothing is stored), so print this summary and bring both.
Preview of what will print:
Sources
Numbers in brackets link to these sources. Every link was checked on October 11, 2026. Some sources are written by people who support a particular approach; we’ve tried to say so in the tags.
- MedlinePlus (U.S. National Library of Medicine). Fatigue. Accessed October 11, 2026. https://medlineplus.gov/ency/article/003088.htm
- MedlinePlus (U.S. National Library of Medicine). Anaphylaxis. Accessed October 11, 2026. https://medlineplus.gov/ency/article/000844.htm
- MedlinePlus. Chest pain. Accessed October 11, 2026. https://medlineplus.gov/ency/article/003079.htm
- MedlinePlus. Asthma. Accessed October 11, 2026. https://medlineplus.gov/ency/article/000141.htm
- MedlinePlus. Fainting. Accessed October 11, 2026. https://medlineplus.gov/ency/article/003092.htm
- National Institute of Mental Health (NIMH). Help for Mental Illnesses. Accessed October 11, 2026. https://www.nimh.nih.gov/health/find-help
- Centers for Disease Control and Prevention (CDC), National Center for Environmental Health. Mold (About mold). Reviewed Sept 26, 2024. Accessed October 11, 2026. https://www.cdc.gov/mold-health/about/index.html
- American Academy of Allergy, Asthma & Immunology (AAAAI). Mold Allergy (patient page; updated July 8, 2026). Accessed October 11, 2026. https://www.aaaai.org/conditions-treatments/allergies/mold-allergy
- Hope J. A review of the mechanism of injury and treatment approaches for illness resulting from exposure to water-damaged buildings, mold, and mycotoxins. ScientificWorldJournal. 2013;2013:767482. PMID: 23710148. Accessed October 11, 2026. https://pmc.ncbi.nlm.nih.gov/articles/PMC3654247/
- Chang C, Gershwin ME. The Myth of Mycotoxins and Mold Injury. Clin Rev Allergy Immunol. 2019;57(3):449-455. PMID: 31608429. Accessed October 11, 2026. https://doi.org/10.1007/s12016-019-08767-4
- Shoemaker R, Johnson K, Jim L, et al. Diagnostic Process for Chronic Inflammatory Response Syndrome (CIRS): A Consensus Statement. Report of the Consensus Committee of Surviving Mold. Internal Medicine Review. 2018;4(5). Accessed October 11, 2026. https://www.survivingmold.com/Publications/CIRS_diagnostic_protocol_final_5_1_2018.pdf
- Bush RK, Portnoy JM, Saxon A, Terr AI, Wood RA. The medical effects of mold exposure (AAAAI position paper). J Allergy Clin Immunol. 2006;117(2):326-333. PMID: 16514772. Accessed October 11, 2026. https://doi.org/10.1016/j.jaci.2005.12.001
- Lee E, Picard M. Diagnosis and management of mast cell activation syndrome (MCAS) in Canada: a practical approach. Allergy Asthma Clin Immunol. 2025;21:49. PMID: 41272881. Accessed October 11, 2026. https://pmc.ncbi.nlm.nih.gov/articles/PMC12639879/
- Molderings GJ, Brettner S, Homann J, Afrin LB. Mast cell activation disease: a concise practical guide for diagnostic workup and therapeutic options. J Hematol Oncol. 2011;4:10. PMID: 21418662. Accessed October 11, 2026. https://pmc.ncbi.nlm.nih.gov/articles/PMC3069946/
- The Mast Cell Disease Society (TMS). Symptoms and Triggers of Mast Cell Activation. Accessed October 11, 2026. https://tmsforacure.org/signs-symptoms-triggers/symptoms-and-triggers-of-mast-cell-activation/
- Dysautonomia International. Postural Orthostatic Tachycardia Syndrome. Accessed October 11, 2026. https://www.dysautonomiainternational.org/page.php?ID=30
- Sheldon RS, Grubb BP, Olshansky B, et al. 2015 Heart Rhythm Society expert consensus statement on the diagnosis and treatment of postural tachycardia syndrome, inappropriate sinus tachycardia, and vasovagal syncope. Heart Rhythm. 2015;12:e41-e63. PMID: 25980576. Accessed October 11, 2026. https://pmc.ncbi.nlm.nih.gov/articles/PMC5267948/
- The Ehlers-Danlos Society. Hypermobile Ehlers-Danlos Syndrome (hEDS). Accessed October 11, 2026. https://www.ehlers-danlos.com/heds/
- Malfait F, Francomano C, Byers P, et al. The 2017 international classification of the Ehlers-Danlos syndromes. Am J Med Genet C Semin Med Genet. 2017;175(1):8-26. PMID: 28306229. Accessed October 11, 2026. https://doi.org/10.1002/ajmg.c.31552
- Shaw BH, Stiles LE, Bourne K, et al. The face of postural tachycardia syndrome - insights from a large cross-sectional online community-based survey. J Intern Med. 2019;286(4):438-448. PMID: 30861229. Accessed October 11, 2026. https://pmc.ncbi.nlm.nih.gov/articles/PMC6790699/
- Hakim A, O'Callaghan C, De Wandele I, et al. Cardiovascular autonomic dysfunction in Ehlers-Danlos syndrome-Hypermobile type. Am J Med Genet C Semin Med Genet. 2017;175(1):168-174. PMID: 28160388. Accessed October 11, 2026. https://doi.org/10.1002/ajmg.c.31543
- Vernino S, Bourne KM, Stiles LE, et al. Postural orthostatic tachycardia syndrome (POTS): State of the science and clinical care from a 2019 National Institutes of Health Expert Consensus Meeting - Part 1. Auton Neurosci. 2021;235:102828. PMID: 34144933. Accessed October 11, 2026. https://pmc.ncbi.nlm.nih.gov/articles/PMC8455420/
- U.S. Environmental Protection Agency (EPA). A Brief Guide to Mold, Moisture and Your Home. Accessed October 11, 2026. https://www.epa.gov/mold/brief-guide-mold-moisture-and-your-home
- The Ehlers-Danlos Society. Diagnostic Criteria for Hypermobile Ehlers-Danlos Syndrome (hEDS) checklist. Accessed October 11, 2026. https://www.ehlers-danlos.com/wp-content/uploads/2017/05/hEDS-Dx-Criteria-checklist-1.pdf
- Fikree A, Chelimsky G, Collins H, Kovacic K, Aziz Q. Gastrointestinal involvement in the Ehlers-Danlos syndromes. Am J Med Genet C Semin Med Genet. 2017;175(1):181-187. PMID: 28186368. Accessed October 11, 2026. https://doi.org/10.1002/ajmg.c.31546
- Chopra P, Tinkle B, Hamonet C, et al. Pain management in the Ehlers-Danlos syndromes. Am J Med Genet C Semin Med Genet. 2017;175(1):212-219. PMID: 28186390. Accessed October 11, 2026. https://doi.org/10.1002/ajmg.c.31554
- Shoemaker RC, House DE. Sick building syndrome (SBS) and exposure to water-damaged buildings: time series study, clinical trial and mechanisms. Neurotoxicol Teratol. 2006;28(5):573-588. PMID: 17010568. Accessed October 11, 2026. https://doi.org/10.1016/j.ntt.2006.07.003
- MedlinePlus. Dizziness. Accessed October 11, 2026. https://medlineplus.gov/ency/article/003093.htm
- Valent P, Akin C, Arock M, et al. Definitions, criteria and global classification of mast cell disorders with special reference to mast cell activation syndromes: a consensus proposal. Int Arch Allergy Immunol. 2012;157(3):215-225. PMID: 22041891. Accessed October 11, 2026. https://pmc.ncbi.nlm.nih.gov/articles/PMC3224511/
- The Ehlers-Danlos Society. What is HSD? Accessed October 11, 2026. https://www.ehlers-danlos.com/what-is-hsd/
- National Heart, Lung, and Blood Institute (NHLBI). Anemia: Symptoms. Last updated March 24, 2022. Accessed October 11, 2026. https://www.nhlbi.nih.gov/health/anemia/symptoms
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Hypothyroidism (Underactive Thyroid). Accessed October 11, 2026. https://www.niddk.nih.gov/health-information/endocrine-diseases/hypothyroidism
- NIDDK. Hyperthyroidism (Overactive Thyroid). Accessed October 11, 2026. https://www.niddk.nih.gov/health-information/endocrine-diseases/hyperthyroidism
- NHLBI. Sleep Apnea: Symptoms. Accessed October 11, 2026. https://www.nhlbi.nih.gov/health/sleep-apnea/symptoms
- National Institute of Mental Health (NIMH). Depression (publication). Accessed October 11, 2026. https://www.nimh.nih.gov/health/publications/depression
- MedlinePlus. Hives. Accessed October 11, 2026. https://medlineplus.gov/ency/article/000845.htm
- MedlinePlus. Abdominal pain. Accessed October 11, 2026. https://medlineplus.gov/ency/article/003120.htm
- MedlinePlus. Joint pain. Accessed October 11, 2026. https://medlineplus.gov/ency/article/003261.htm
- Job Accommodation Network (JAN). Multiple Chemical Sensitivity. Web page, accessed October 14, 2026. https://askjan.org/disabilities/Multiple-Chemical-Sensitivity.cfm
- Steinemann A. National prevalence and effects of multiple chemical sensitivities. J Occup Environ Med. 2018;60(3):e152-e156. PMID: 29329146. https://pmc.ncbi.nlm.nih.gov/articles/PMC5865484/
- Multiple chemical sensitivity: a 1999 consensus. Arch Environ Health. 1999;54(3):147-149. PMID: 10444033. https://doi.org/10.1080/00039899909602251
- American Academy of Allergy, Asthma and Immunology (AAAAI) Board of Directors. Idiopathic environmental intolerances (position statement). J Allergy Clin Immunol. 1999;103(1 Pt 1):36-40. PMID: 9893182. https://www.aaaai.org/Aaaai/media/MediaLibrary/PDF%20Documents/Practice%20and%20Parameters/Idiopathic-environmental-intolerances-1999.pdf
- American College of Occupational and Environmental Medicine (ACOEM). Multiple chemical sensitivities: idiopathic environmental intolerance (position statement). J Occup Environ Med. 1999;41(11):940-942. https://journals.lww.com/joem/fulltext/1999/11000/multiple_chemical_sensitivities__idiopathic.3.aspx